Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746899 | 0.86 | KDM4E (0.48) | SMN1; SMN2ALDH1A1KDM4EGAAPDE3B | |
| SCHEMBL6746858 | 0.85 | KMT2A (0.37) | LTA4HSMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL6743776 | 0.73 | L3MBTL1 (0.44) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL6745452 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL28034661 | 0.70 | CYP1A2 (0.47) | ALDH1A1KDM4ECYP1A2GAANPSR1 | |
| SCHEMBL24936702 | 0.66 | TDP1 (0.51) | CYSLTR2CYSLTR1LTA4HALDH1A1L3MBTL1 | |
| SCHEMBL4457893 | 0.66 | LTA4H (0.48) | CYSLTR2CYSLTR1LTA4HALDH1A1L3MBTL1 | |
| SCHEMBL3951838 | 0.65 | L3MBTL1 (0.66) | LTA4HKDM4EL3MBTL1RAB9A | |
| SCHEMBL38664 | 0.65 | LTA4H (0.60) | LTA4HSMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL7692040 | 0.64 | LTA4H (0.52) | CYSLTR2CYSLTR1LTA4HL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | disclosed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| CN-1420873-A | Substituted phenyluracils | BAYER AG (DE) | 2003-05-28 | — | — | CN | disclosed |
| EP-1272478-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | disclosed |
| WO-2001077084-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173425-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | CYSLTR2 3919/4885CYSLTR1 3628/4885LTA4H 4639/4885 |
| US-20040023805-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | CYSLTR2 3919/4885CYSLTR1 3628/4885LTA4H 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.