Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746815 | 0.90 | PTGS2 (0.42) | PTGS2PTGS1LMNAMAPTHTT | |
| SCHEMBL6745050 | 0.86 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL6749852 | 0.84 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8974723 | 0.82 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL6745443 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6746211 | 0.81 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6746439 | 0.80 | CASP1 (0.39) | PTGS2PTGS1HTT | |
| SCHEMBL6750004 | 0.80 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6735438 | 0.78 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL6746730 | 0.78 | PTGS2 (0.38) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |