SCHEMBL6744360

SCHEMBL6744360

CCCC(N1CCN(CC)CCN(CC)CC1)N1CCN(CC)CCN(CC)CC1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
HTT P42858 1/20 0.35
CHRNA7 P36544 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
KDM4E B2RXH2 4/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
RAD52 P43351 1/20 0.31
GFER P55789 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6742560 0.86 MEN1 (0.40) ALDH1A1HTTCHRNA7KMT2AMEN1
SCHEMBL6746357 0.84 DRD2 (0.38)
SCHEMBL13632435 0.81 HRH3 (0.35) ALDH1A1HTTCHRNA7KMT2AMEN1
SCHEMBL6740215 0.80 CHRNA7 (0.35) ALDH1A1CHRNA7KMT2AMEN1KDM4E
SCHEMBL19629041 0.79 KDM4E (0.40) ALDH1A1HTTCHRNA7KMT2AMEN1
SCHEMBL6745237 0.78 KDM4E (0.32) ALDH1A1CHRNA7KDM4EMAPT
SCHEMBL16972740 0.78 CHRM2 (0.34) ALDH1A1KDM4E
SCHEMBL23921031 0.77 ALDH1A1 (0.33) ALDH1A1HTTCHRNA7KMT2AMEN1
SCHEMBL4389412 0.77 KDM4E (0.33) ALDH1A1HTTCHRNA7KMT2AMEN1
SCHEMBL5709265 0.77 SLC6A3 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689919-B1 SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-02-10 US disclosed