SCHEMBL6745237

SCHEMBL6745237

CCCC(N1CCN(C(C)C)CCN(C(C)C)CC1)N1CCN(C(C)C)CCN(C(C)C)CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
CHRNA7 P36544 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6746315 0.86 DNM1 (0.32) KDM4EALDH1A1MAPTPKMCHRNA7
SCHEMBL16972740 0.80 CHRM2 (0.34) KDM4EALDH1A1
SCHEMBL17327897 0.80 HRH3 (0.36) KDM4EALDH1A1MAPTPKMCHRNA7
SCHEMBL20796436 0.80 KDM4E (0.35) KDM4EALDH1A1MAPTPKMCHRNA7
SCHEMBL5709265 0.79 SLC6A3 (0.39)
SCHEMBL6744360 0.78 ALDH1A1 (0.35) KDM4EALDH1A1MAPTCHRNA7
SCHEMBL7330270 0.77 SLC6A3 (0.38)
SCHEMBL6746357 0.76 DRD2 (0.38)
SCHEMBL6744276 0.75
SCHEMBL19632400 0.75 SIGMAR1 (0.35) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689919-B1 SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-02-10 US disclosed