Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747579 | 0.91 | ICAM1 (1.00) | ICAM1VCAM1 | |
| Hydrochloric Acid SCHEMBL6749074 | 0.90 | ICAM1 (0.98) | ICAM1VCAM1 | |
| SCHEMBL8318910 | 0.89 | ICAM1 (0.96) | ICAM1VCAM1 | |
| Sulfuric Acid SCHEMBL6749617 | 0.88 | ICAM1 (0.93) | ICAM1VCAM1 | |
| SCHEMBL6747371 | 0.86 | ICAM1 (0.90) | ICAM1VCAM1 | |
| SCHEMBL7147635 | 0.86 | ICAM1 (0.83) | ICAM1VCAM1 | |
| SCHEMBL6749067 | 0.83 | ICAM1 (0.81) | ICAM1VCAM1 | |
| SCHEMBL6747385 | 0.83 | ICAM1 (0.73) | ICAM1VCAM1 | |
| SCHEMBL6747297 | 0.83 | ICAM1 (0.73) | ICAM1VCAM1 | |
| SCHEMBL6747316 | 0.81 | ICAM1 (0.73) | ICAM1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | ICAM1 412/4885VCAM1 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.