Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745968 | 1.00 | ALDH1A1 (0.42) | ALDH1A1SGMS2TSHRKDM4ETRPM8 | |
| Azoxystrobin SCHEMBL55087 | 0.90 | MAP4K4 (0.38) | ALDH1A1TSHR | |
| Azoxystrobin SCHEMBL29362394 | 0.90 | MAP4K4 (0.38) | ALDH1A1TSHR | |
| Azoxystrobin SCHEMBL4447188 | 0.90 | MAP4K4 (0.38) | ALDH1A1TSHR | |
| Azoxystrobin SCHEMBL4113006 | 0.90 | MAP4K4 (0.38) | ALDH1A1TSHR | |
| Azoxystrobin SCHEMBL18823 | 0.90 | MAP4K4 (0.38) | ALDH1A1TSHR | |
| Azoxystrobin SCHEMBL17701154 | 0.89 | MAP4K4 (0.38) | ALDH1A1TSHR | |
| Azoxystrobin SCHEMBL17701140 | 0.87 | PIN1 (0.37) | ALDH1A1TSHR | |
| Azoxystrobin SCHEMBL4938235 | 0.85 | ALDH1A1 (0.33) | ALDH1A1SGMS2TSHR | |
| Azoxystrobin SCHEMBL6424745 | 0.84 | PIN1 (0.36) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777412-B2 | PYRIMIDIN-4-YLOXY)PHENYL)-3-METHOXYPROPENOATE DERIVATIVES | SYNGENTA LIMITED (GB) | 2004-08-17 | — | — | US | disclosed |
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | CLOUGH JOHN MARTIN (GB) | 2004-05-13 | — | — | US | disclosed |
| US-6613773-B2 | Pyrimidinyloxyphenyl-3-alkoxypropenoates derivatives | SYNGENTA LIMITED (GB) | 2003-09-02 | — | — | US | disclosed |
| US-20030060626-A1 | Fungicides | SYNGENTA LIMITED (GB) | 2003-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | DDT, SQOR, TH | ALDH1A1 482/4885SGMS2 2586/4885TSHR 946/4885 |
| US-20030060626-A1 | Fungicides | CYP51A1, CYP1A1, CYP1A2 | ALDH1A1 301/4885SGMS2 2438/4885TSHR 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.