SCHEMBL6746625

SCHEMBL6746625

N#CCC(O)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.44
MAOB P27338 2/20 0.44
CYP1A2 P05177 1/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CTSS P25774 3/20 0.41
CTSK P43235 2/20 0.41
EPHX1 P07099 1/20 0.41
CTSC P53634 2/20 0.40
SRR Q9GZT4 1/20 0.40
CTSL P07711 3/20 0.40
CTSB P07858 1/20 0.40
ALPI P09923 1/20 0.39
PKM P14618 1/20 0.39
PTGS1 P23219 1/20 0.39
XIAP P98170 1/20 0.39
SLC7A5 Q01650 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11856064 0.82 CTSB (0.38) ESR1ESR2CTSSCTSLCTSB
SCHEMBL4980139 0.80 DPP4 (0.45) CTSSCTSKCTSC
SCHEMBL11857401 0.79 ATM (0.47) CTSSCTSKCTSLCTSBPTGS1
SCHEMBL1833635 0.79 TRPA1 (0.55) TRPA1CYP1A2EPHX1SRRALPI
SCHEMBL15195458 0.79 CYP1A2 (0.47) TRPA1MAOBCYP1A2EPHX1SRR
SCHEMBL9014783 0.79 CYP1A2 (0.47) TRPA1MAOBCYP1A2EPHX1SRR
SCHEMBL22868014 0.78 MAOB (0.47) MAOBCYP1A2ESR1ESR2CTSS
SCHEMBL10431094 0.77 CSNK1E (0.51) TRPA1EPHX1CTSCALPIPKM
SCHEMBL11829664 0.77 MAOB (0.46) MAOBESR1ESR2
Ammonia Solution, Strong SCHEMBL29021310 0.77 TRPA1 (0.53) TRPA1CYP1A2EPHX1SRRALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1260345-C Novel microorganisms and process for producing DAICEL CHEM (JP) 2006-06-21 CN disclosed
US-6699695-B1 FOR EXAMPLE, CONVERTING 2-HYDROXY-4-METHYLTHIOBUTYRONITRILE INTO THE CORRESPONDING AMIDE, WHICH IS A PRECURSOR TO THE FEED SUPPLEMENT 2-HYDROXY-4-METHYLTHIOBUTYRIC ACID DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-03-02 US disclosed
CN-1290296-A Novel microorganisms and process for producing DAICEL CHEM (JP) 2001-04-04 CN disclosed
EP-1055724-A1 MICROORGANISMS AND PROCESS FOR PRODUCING AMIDE COMPOUNDS Daicel Chemical Industries, Ltd. (JP) 2000-11-29 EP disclosed
EP-0357545-A2 Cationic compounds, their preparation and their use in the photochemical stabilisation of basic dyeable polyamide polyacrylonitrile and polyester fibres CIBA-GEIGY AG (CH) 1990-03-07 EP disclosed