Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902774 | 0.85 | MMP12 (0.52) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL3938461 | 0.84 | MMP12 (0.51) | DPP4MMP12MMP13MMP2MMP9 | |
| SCHEMBL1139615 | 0.84 | MMP12 (0.51) | DPP4MMP12MMP13MMP2MMP9 | |
| SCHEMBL28525077 | 0.81 | MMP12 (0.48) | DPP4MMP12MMP13MMP2MMP9 | |
| SCHEMBL4799370 | 0.81 | MMP2 (0.55) | DPP4MMP12MMP13MMP2MMP9 | |
| SCHEMBL6695127 | 0.81 | MIF (0.46) | DPP4MMP12MMP13MMP2MMP9 | |
| SCHEMBL15195459 | 0.81 | DPP4 (0.45) | DPP4MMP12MMP13MMP2MMP9 | |
| SCHEMBL6746625 | 0.80 | TRPA1 (0.44) | CTSCCTSSCTSK | |
| SCHEMBL9641133 | 0.78 | MMP12 (0.49) | DPP4MMP12MMP13MMP2MMP9 | |
| SCHEMBL112302 | 0.77 | POLB (0.45) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355061-B2 | Method of manufacturing cyano compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-04-08 | — | — | US | disclosed |
| US-20050004388-A1 | Method of manufacturing cyano compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004388-A1 | Method of manufacturing cyano compounds | HBB, IDH1, NOX3 | DPP4 3143/4885MMP12 3664/4885MMP13 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.