Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749869 | 0.89 | DHODH (0.42) | CBFBTRPV1FEN1CTSDBACE1 | |
| SCHEMBL6726003 | 0.88 | PTGS2 (0.41) | PTGS2CBFBABL1TRPV1BCR | |
| SCHEMBL6744770 | 0.85 | KIF11 (0.43) | PTGS2TRPV1PTGS1FEN1ALOX5AP | |
| SCHEMBL6834690 | 0.84 | PTGS2 (0.45) | PTGS2ABL1TRPV1BCRPTGS1 | |
| SCHEMBL6746852 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1FEN1ALOX5APCA1 | |
| SCHEMBL6746002 | 0.84 | PTGS2 (0.41) | PTGS2TRPV1PTGS1FEN1ALOX5AP | |
| SCHEMBL6747337 | 0.84 | FEN1 (0.38) | PTGS2TRPV1PTGS1FEN1ALOX5AP | |
| SCHEMBL6746225 | 0.83 | PTGS2 (0.43) | PTGS2PTGS1FEN1ALOX5APCA1 | |
| SCHEMBL6743148 | 0.83 | PTGS2 (0.51) | PTGS2ABL1PTGS1FEN1ALOX5AP | |
| SCHEMBL6743053 | 0.82 | PTGS2 (0.41) | PTGS2CBFBABL1TRPV1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |