Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143509 | 0.75 | CYP2D6 (0.52) | CYP2D6L3MBTL1CHRM2OPRL1CHRM3 | |
| SCHEMBL6750542 | 0.74 | OPRM1 (0.54) | CYP2D6OPRL1CYP3A4POLBHSD17B10 | |
| SCHEMBL23145284 | 0.74 | ACHE (0.53) | CYP2D6CHRM2OPRL1CHRM3CYP3A4 | |
| SCHEMBL6749273 | 0.74 | CYP2D6 (0.61) | CYP2D6L3MBTL1CHRM2OPRL1CHRM3 | |
| SCHEMBL16862697 | 0.72 | CYP2D6 (0.56) | CYP2D6CHRM2OPRL1CHRM3CYP3A4 | |
| SCHEMBL1147211 | 0.72 | OPRL1 (0.63) | CYP2D6CHRM2OPRL1CHRM3CYP3A4 | |
| SCHEMBL28548988 | 0.71 | OPRL1 (0.71) | CYP2D6CHRM2OPRL1CHRM3CYP3A4 | |
| SCHEMBL1269458 | 0.71 | CYP2D6 (0.61) | CYP2D6CHRM2OPRL1CHRM3CYP3A4 | |
| SCHEMBL1975609 | 0.71 | CYP2D6 (0.57) | CYP2D6CHRM2OPRL1CHRM3CYP3A4 | |
| Hydrochloric Acid SCHEMBL25235306 | 0.71 | POLB (0.64) | CYP2D6CHRM2OPRL1CHRM3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | CYP2D6 32/4885L3MBTL1 4411/4885CHRM2 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.