SCHEMBL6749568

SCHEMBL6749568

CCCO[SiH](OCCC)c1ccc2cc3cc4ccccc4cc3cc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
GPBAR1 Q8TDU6 3/20 0.35
CYSLTR1 Q9Y271 2/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HBB P68871 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28455764 0.95 CYP1A2 (0.41) CYP1A2CYP2A6PPARGPPARAGPBAR1
SCHEMBL6746762 0.86 CYP2A6 (0.38) CYP1A2CYP2A6PPARGPPARAALDH1A1
SCHEMBL15066853 0.80 CYP2A6 (0.44) CYP1A2CYP2A6PPARGPPARAALDH1A1
SCHEMBL6746751 0.79 ALDH1A1 (0.38) CYP1A2GPBAR1CYSLTR1ALDH1A1CYP3A4
SCHEMBL2950776 0.77 KMT2A (0.37) ALDH1A1LMNAMEN1KMT2A
SCHEMBL6744233 0.77 ALDH1A1 (0.34) CYP1A2ALDH1A1TDP1HSD17B10CYP2C9
SCHEMBL704584 0.77 ALDH1A1 (0.35) ALDH1A1TDP1SLC6A2LMNAMEN1
SCHEMBL6750036 0.76 HTR2A (0.37) CYP1A2GPBAR1CYSLTR1ALDH1A1HIF1A
SCHEMBL313696 0.75 LMNA (0.44) ALDH1A1CYP3A4TDP1MAPK1LMNA
SCHEMBL3337785 0.73 LTA4H (0.46) ALDH1A1TDP1HSD17B10KDM4ECETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 CYP1A2 2466/4885CYP2A6 4100/4885PPARG 3940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.