Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.38 |
| ▸ | FEN1 | P39748 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718990 | 0.86 | SCN9A (0.44) | SCN9APTGES2ALOX5APFEN1GAA | |
| SCHEMBL6834757 | 0.85 | CA1 (0.45) | SCN9APTGES2CA1CA2PTGS2 | |
| SCHEMBL6744930 | 0.83 | TGFBR1 (0.39) | ALOX5APFEN1CA1CA2GAA | |
| SCHEMBL6746037 | 0.82 | ALOX5AP (0.44) | ALOX5APFEN1CA1CA2GAA | |
| SCHEMBL6746699 | 0.82 | TGFBR1 (0.43) | ALOX5APFEN1CA1CA2PTGS2 | |
| SCHEMBL6749607 | 0.81 | SCN9A (0.40) | SCN9APTGES2ALOX5APFEN1CA1 | |
| SCHEMBL6749867 | 0.78 | PTGS2 (0.49) | ALOX5APFEN1CA1CA2PTGS2 | |
| SCHEMBL6744782 | 0.78 | CA1 (0.39) | ALOX5APFEN1CA1CA2PTGS2 | |
| SCHEMBL7045462 | 0.78 | SCN9A (0.45) | SCN9AALOX5APFEN1PTGS2HTT | |
| SCHEMBL6841185 | 0.77 | PTGES2 (0.41) | SCN9APTGES2CA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |