Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141162 | 0.84 | ALDH1A1 (0.41) | ALDH1A1ADRA1DADRA1AADRA1BDUT | |
| SCHEMBL20391402 | 0.82 | DUT (0.42) | ALDH1A1ADRA1DADRA1AADRA1BDUT | |
| SCHEMBL9900205 | 0.75 | ADRA1D (0.43) | ALDH1A1ADRA1DADRA1AADRA1BDPP4 | |
| SCHEMBL3127757 | 0.75 | KDM4E (0.37) | ALDH1A1ADRA1DADRA1AADRA1BDUT | |
| SCHEMBL9031589 | 0.75 | LMNA (0.36) | DUTBACE1POLB | |
| SCHEMBL17410506 | 0.74 | BACE1 (0.34) | ALDH1A1BACE1CYP2A6 | |
| SCHEMBL3584022 | 0.73 | MRGPRX4 (0.45) | ALDH1A1BACE1MAPTHPGD | |
| SCHEMBL9900646 | 0.73 | L3MBTL1 (0.36) | BACE1CYP2C9CYP2C19POLB | |
| SCHEMBL5340854 | 0.73 | LMNA (0.45) | ALDH1A1BACE1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL163740 | 0.73 | MAPT (0.40) | ALDH1A1BACE1POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703373-B1 | ANTICARCINOGENIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-09 | — | — | US | disclosed |