Sugi Predict

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SCHEMBL675130

SCHEMBL675130

Cn1cc(C(=O)Nc2ccccc2-c2ccc(F)cc2F)c(C(F)(F)F)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.51
▸ POLB P06746 1/20 0.51
▸ NTRK1 P04629 2/20 0.48
▸ CHRM3 P20309 3/20 0.48
▸ WDR5 P61964 2/20 0.45
▸ GAA P10253 3/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ MAPT P10636 1/20 0.43
▸ ATM Q13315 1/20 0.42
▸ STING1 Q86WV6 1/20 0.42
▸ TP53 P04637 1/20 0.42
▸ BACE1 P56817 2/20 0.42
▸ BACE2 Q9Y5Z0 2/20 0.42
▸ CYP1A2 P05177 2/20 0.42
▸ CYP3A4 P08684 2/20 0.42
▸ CYP2D6 P10635 2/20 0.42
▸ CYP2C9 P11712 2/20 0.42
▸ CYP2C19 P33261 2/20 0.42
▸ NPSR1 Q6W5P4 2/20 0.42
▸ HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419095 0.92 LMNA (0.54) LMNAPOLBNTRK1WDR5GAA
SCHEMBL120547 0.92 LMNA (0.54) LMNAPOLBNTRK1WDR5GAA
SCHEMBL17144786 0.92 LMNA (0.53) LMNAPOLBNTRK1WDR5GAA
SCHEMBL4445834 0.91 LMNA (0.50) LMNAPOLBNTRK1CHRM3WDR5
SCHEMBL303186 0.90 LMNA (0.56) LMNAPOLBNTRK1CHRM3WDR5
SCHEMBL4447678 0.90 LMNA (0.60) LMNAPOLBNTRK1CHRM3WDR5
SCHEMBL15063349 0.90 LMNA (0.51) LMNAPOLBNTRK1CHRM3WDR5
SCHEMBL29390999 0.89 LMNA (0.53) LMNAPOLBNTRK1CHRM3WDR5
SCHEMBL1085546 0.89 LMNA (0.53) LMNAPOLBNTRK1CHRM3WDR5
SCHEMBL4446436 0.88 LMNA (0.47) LMNAPOLBNTRK1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 — — EP claimed
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES BASF SE (DE) 2015-03-19 — — US claimed
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2014-06-26 — — US claimed
US-20130267414-A1 PESTICIDAL MIXTURES BASF SE (DE) 2013-10-10 — — US claimed
US-20130137571-A1 Crystalline Modification of Fipronil BASF SE (DE) 2013-05-30 — — US claimed
EP-2489264-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a carboxamide fungicide BASF SE (DE) 2012-08-22 — — EP claimed
EP-2489263-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 — — EP claimed
JP-2011527306-A — — 2011-10-27 — — JP claimed
US-20110159107-A1 Pesticidal Mixtures Comprising Isoxazoline Compounds II BASF SE (DE) 2011-06-30 — — US claimed
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram BASF SE (DE) 2011-06-30 — — US claimed
WO-2009065834-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2009-05-28 — — WO claimed
WO-2009062905-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-05-22 — — WO claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 — — WO claimed
WO-2009063076-A2 FUNGICIDAL MIXTURES III BASF SE (DE) 2009-05-22 — — WO claimed
WO-2009063074-A2 FUNGICIDAL MIXTURES I BASF SE (DE) 2009-05-22 — — WO claimed
US-20090042724-A1 Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides BASF AKTIENGESELLSCHAFT (DE) 2009-02-12 — — US claimed
WO-2009007233-A2 PESTICIDAL MIXTURES COMPRISING SULFONAMIDES AND ONE OR MORE FUNGICIDES BASF SE (DE) 2009-01-15 — — WO claimed
WO-2008148859-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2008-12-11 — — WO claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 — — WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267414-A1 PESTICIDAL MIXTURES AADAC, CTRL, AAAS LMNA 3546/4885POLB 4261/4885NTRK1 4662/4885
US-20110159107-A1 Pesticidal Mixtures Comprising Isoxazoline Compounds II PRDX1, PRDX2, PRDX5 LMNA 3855/4885POLB 4374/4885NTRK1 3593/4885
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CPN1, SRM, STS LMNA 3355/4885POLB 3649/4885NTRK1 4284/4885
US-20090042724-A1 Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides CBR3, CBR1, SNU13 LMNA 3266/4885POLB 3502/4885NTRK1 3708/4885
US-20130137571-A1 Crystalline Modification of Fipronil FIP1L1, PTMS, FIBP LMNA 2209/4885POLB 4375/4885NTRK1 3963/4885
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram CHRM3, CHRM2, BRS3 LMNA 2976/4885POLB 4836/4885NTRK1 2088/4885
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES AADAC, AS3MT, DDT LMNA 4360/4885POLB 4562/4885NTRK1 4224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.