SCHEMBL675134

SCHEMBL675134

Cc1ccc(-c2ccc(=O)[nH]n2)cc1-c1cc(Cl)cc(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
PDE4A P27815 3/20 0.49
PDE4B Q07343 3/20 0.49
PDE4C Q08493 3/20 0.49
PDE4D Q08499 3/20 0.49
PDE3B Q13370 6/20 0.47
PDE3A Q14432 6/20 0.47
CYP1A2 P05177 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7584622 0.82 CYP1A2 (0.58) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL11736972 0.81 LMNA (0.60) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL12595727 0.79 LMNA (0.66) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL11740736 0.78 LMNA (0.60) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL675133 0.78 KMT2A (0.53) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL12595734 0.75 LMNA (0.60) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL3346610 0.75 LMNA (0.60) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL11736483 0.75 LMNA (0.60) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL1769717 0.74 NOTUM (0.57) LMNAKMT2AMEN1PDE4APDE4B
SCHEMBL4048920 0.74 CYP1A2 (0.62) LMNAKMT2AMEN1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2022-06-02 US disclosed
EP-3927341-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2021-12-29 EP disclosed
US-10899932-B2 Non-amphoteric, quaternisable and water-soluble polymers for modifying the surface charge of solid particles BASF SE (DE) 2021-01-26 US disclosed
WO-2020201440-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2020-10-08 WO disclosed
US-10759767-B2 Compositions comprising a triazole compound BASF Agro B.V. (NL) 2020-09-01 US disclosed
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 EP disclosed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 EP disclosed
EP-3498098-A1 COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2019-06-19 EP disclosed
US-20180334569-A9 NON-AMPHOTERIC, QUATERNISABLE AND WATER-SOLUBLE POLYMERS FOR MODIFYING THE SURFACE CHARGE OF SOLID PARTICLES BASF SE (DE) 2018-11-22 US disclosed
US-20180296459-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS BASF SE (DE) 2018-10-18 US disclosed
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides BASF SE (DE) 2008-10-16 US disclosed
US-20080249113-A1 Fungicidal Mixtures BASF AKITENGESELLSCHAFT (DE) 2008-10-09 US disclosed
US-20080153701-A1 Fungicidal Mixtures BASF AKTIENGESELLSCHAFT (DE) 2008-06-26 US disclosed
EP-1898703-A1 FUNGICIDE MIXTURES BASED ON 2,4-DISUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYLAMIDES BASF SE (DE) 2008-03-19 EP disclosed
EP-1898704-A1 FUNGICIDAL MIXTURES BASED ON 2,5-DISUBSTITUTED PYRAZOL CARBOXYLIC ACID BIPHENYLAMIDES BASF SE (DE) 2008-03-19 EP disclosed
EP-1813152-A1 Fungicidal mixture based on 3,4-disubstituted biphenylanilides BASF AKTIENGESELLSCHAFT (DE) 2007-08-01 EP disclosed
EP-1813151-A1 Fungicidal compositions based on 1-methyl-pyrazol-4-yl-anilides BASF Aktiengesellschaft (DE) 2007-08-01 EP disclosed
WO-2007003540-A1 FUNGICIDAL MIXTURES BASED ON 2,5-DISUBSTITUTED PYRAZOL CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 WO disclosed
WO-2007000462-A1 FUNGICIDE MIXTURES BASED ON 2,4-DISUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-04 WO disclosed
EP-0453137-A2 Aminopyrimidine derivatives, a process for production thereof, and uses thereof NIHON NOHYAKU CO., LTD. (JP) 1991-10-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249113-A1 Fungicidal Mixtures ARSA, DDT, AZI2 LMNA 3650/4885KMT2A 917/4885MEN1 2723/4885
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST P2RX7, CAT, PDE8A LMNA 2657/4885KMT2A 1069/4885MEN1 2904/4885
US-20080255107-A1 Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides CBR3, CBR1, NAT1 LMNA 2193/4885KMT2A 3199/4885MEN1 3594/4885
US-20180296459-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS PUF60, POLR1C, PICALM LMNA 2122/4885KMT2A 4325/4885MEN1 1605/4885
US-20080153701-A1 Fungicidal Mixtures STS, DDT, CYP4X1 LMNA 2041/4885KMT2A 2136/4885MEN1 196/4885
US-10759767-B2 Compositions comprising a triazole compound CYP1B1, CYP3A5, CYP4B1 LMNA 3497/4885KMT2A 2664/4885MEN1 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.