Sugi Predict

Sugi Predict / Compounds / SCHEMBL675133

SCHEMBL675133

SCHEMBL675133

Cc1ccc(-c2ccc(=O)[nH]n2)c(-c2cc(Cl)cc(Cl)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.53
▸ LMNA P02545 3/20 0.53
▸ MEN1 O00255 3/20 0.53
▸ CYP1A2 P05177 2/20 0.41
▸ PDE4B Q07343 2/20 0.40
▸ PDE4A P27815 1/20 0.40
▸ PDE4C Q08493 1/20 0.40
▸ PDE4D Q08499 1/20 0.40
▸ PDE3A Q14432 3/20 0.38
▸ PDE3B Q13370 2/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ GFER P55789 1/20 0.37
▸ NPC1 O15118 3/20 0.37
▸ RAB9A P51151 3/20 0.37
▸ ALPL P05186 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ HPGD P15428 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ USP2 O75604 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7584622 0.78 CYP1A2 (0.58) KMT2ALMNAMEN1CYP1A2PDE4B
SCHEMBL675134 0.78 LMNA (0.53) KMT2ALMNAMEN1CYP1A2PDE4B
SCHEMBL5504042 0.77 LMNA (0.59) KMT2ALMNAMEN1CYP1A2PDE4B
SCHEMBL10976131 0.76 MEN1 (0.57) KMT2ALMNAMEN1CYP1A2PDE4B
SCHEMBL31703168 0.71 ALPL (0.56) KMT2ALMNAALPLAKR1B1POLB
SCHEMBL7179899 0.71 LMNA (0.54) KMT2ALMNAMEN1CYP1A2PDE4B
SCHEMBL11035831 0.70 LMNA (1.00) KMT2ALMNAMEN1CYP1A2PDE4B
SCHEMBL28165594 0.69 GRM5 (0.40) SMN1; SMN2NPC1RAB9AHPGDMAPT
SCHEMBL11121937 0.69 KMT2A (0.48) KMT2ALMNAMEN1NPC1RAB9A
SCHEMBL21550 0.68 LMNA (0.59) KMT2ALMNAMEN1CYP1A2PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2022-06-02 — — US disclosed
EP-3927341-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2021-12-29 — — EP disclosed
US-10899932-B2 Non-amphoteric, quaternisable and water-soluble polymers for modifying the surface charge of solid particles BASF SE (DE) 2021-01-26 — — US disclosed
WO-2020201440-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2020-10-08 — — WO disclosed
US-10759767-B2 Compositions comprising a triazole compound BASF Agro B.V. (NL) 2020-09-01 — — US disclosed
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 — — EP disclosed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 — — EP disclosed
EP-3498098-A1 COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2019-06-19 — — EP disclosed
US-20180334569-A9 NON-AMPHOTERIC, QUATERNISABLE AND WATER-SOLUBLE POLYMERS FOR MODIFYING THE SURFACE CHARGE OF SOLID PARTICLES BASF SE (DE) 2018-11-22 — — US disclosed
US-20180296459-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS BASF SE (DE) 2018-10-18 — — US disclosed
WO-2007003564-A1 FUNGICIDE MIXTURES BASED ON 3,5-DISUBSTITUTED PYRAZOL-CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 — — WO disclosed
WO-2007003603-A2 FUNGICIDE MIXTURES BASED ON 3-MONOSUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYL AMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 — — WO disclosed
WO-2007003540-A1 FUNGICIDAL MIXTURES BASED ON 2,5-DISUBSTITUTED PYRAZOL CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 — — WO disclosed
WO-2007003643-A1 FUNGICIDAL MIXTURES BASED ON 3,4-DISUBSTITUTED PYRAZOLECARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 — — WO disclosed
WO-2007000462-A1 FUNGICIDE MIXTURES BASED ON 2,4-DISUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-04 — — WO disclosed
EP-1732388-A1 TERNARY FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2006-12-20 — — EP disclosed
WO-2006069716-A1 FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2006-07-06 — — WO disclosed
WO-2005110080-A2 FUNGICIDAL MIXTURES AND NOVEL TRIAZOLOPYRIMIDINES BASF AKTIENGESELLSCHAFT (DE) 2005-11-24 — — WO disclosed
WO-2005094583-A1 TERNARY FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2005-10-13 — — WO disclosed
EP-0453137-A2 Aminopyrimidine derivatives, a process for production thereof, and uses thereof NIHON NOHYAKU CO., LTD. (JP) 1991-10-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST P2RX7, CAT, PDE8A KMT2A 1069/4885LMNA 2657/4885MEN1 2904/4885
US-20180296459-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS PUF60, POLR1C, PICALM KMT2A 4325/4885LMNA 2122/4885MEN1 1605/4885
US-10759767-B2 Compositions comprising a triazole compound CYP1B1, CYP3A5, CYP4B1 KMT2A 2664/4885LMNA 3497/4885MEN1 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.