Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149891 | 0.86 | ALDH1A1 (0.35) | ICAM1POLBALDH1A1TDP1KDM4E | |
| SCHEMBL7149885 | 0.80 | ICAM1 (0.53) | ICAM1POLBALDH1A1KDM4EKMT2A | |
| SCHEMBL6749892 | 0.68 | ALDH1A1 (0.36) | ALDH1A1TDP1KDM4E | |
| SCHEMBL8315505 | 0.64 | HDAC6 (0.45) | POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL8322460 | 0.63 | ICAM1 (0.40) | ICAM1KMT2AMEN1 | |
| SCHEMBL6857064 | 0.62 | MAPT (0.43) | ICAM1 | |
| SCHEMBL6747276 | 0.61 | HDAC6 (0.42) | ICAM1 | |
| SCHEMBL6749176 | 0.61 | LMNA (0.47) | POLBALDH1A1TDP1KDM4EKMT2A | |
| SCHEMBL6745548 | 0.60 | HDAC6 (0.36) | ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6747666 | 0.60 | KDM4E (0.40) | ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | ICAM1 412/4885POLB 2838/4885ALDH1A1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.