Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 12/20 | 0.78 |
| ▸ | MMP1 | P03956 | 12/20 | 0.78 |
| ▸ | MMP9 | P14780 | 10/20 | 0.78 |
| ▸ | MMP3 | P08254 | 10/20 | 0.78 |
| ▸ | MMP7 | P09237 | 10/20 | 0.78 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265752 | 0.91 | MMP1 (0.78) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL6338650 | 0.91 | MMP1 (0.78) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL6337331 | 0.90 | MMP1 (0.76) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL6337327 | 0.90 | MMP1 (0.76) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL6339415 | 0.90 | MMP1 (0.76) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL6339411 | 0.90 | MMP1 (0.76) | MMP13MMP1MMP9MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL6337867 | 0.89 | MMP1 (0.74) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL6283507 | 0.89 | MMP1 (0.60) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL7762105 | 0.83 | MMP1 (0.80) | MMP13MMP1MMP9MMP3MMP7 | |
| SCHEMBL7341460 | 0.83 | MMP1 (0.80) | MMP13MMP1MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229817-A1 | Inhibitors of Hepatitis C virus, compositions and treatments using the same | AGOURON PHARMACEUTICALS, INC. | 2004-11-18 | — | — | US | claimed |
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | claimed |
| US-20040235952-A1 | Inhibitors of severe acute respiratory syndrome (SARS) 3C-like proteinase | AGOURON PHARMACEUTICALS, INC. | 2004-11-25 | — | — | US | disclosed |
| US-20040229817-A1 | Inhibitors of Hepatitis C virus, compositions and treatments using the same | AGOURON PHARMACEUTICALS, INC. | 2004-11-18 | — | — | US | disclosed |
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229817-A1 | Inhibitors of Hepatitis C virus, compositions and treatments using the same | TIMP3, MMP2, MMP7 | MMP13 6/4885MMP1 10/4885MMP9 14/4885 |
| US-20040235952-A1 | Inhibitors of severe acute respiratory syndrome (SARS) 3C-like proteinase | ACE, ACE2, PRSS3 | MMP13 108/4885MMP1 433/4885MMP9 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.