Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 15/20 | 0.60 |
| ▸ | FAAH | O00519 | 6/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755043 | 0.83 | MGLL (0.62) | MGLLFAAHNPSR1HSP90AA1TDP1 | |
| SCHEMBL24452258 | 0.81 | MGLL (0.60) | MGLLFAAHNPSR1HSP90AA1TDP1 | |
| SCHEMBL14750493 | 0.81 | MGLL (0.61) | MGLLFAAHNPSR1HSP90AA1TDP1 | |
| Hydrochloric Acid SCHEMBL6753371 | 0.81 | MGLL (0.60) | MGLLFAAHNPSR1HSP90AA1TDP1 | |
| Hydrazine SCHEMBL16908509 | 0.80 | MGLL (0.58) | MGLLFAAHNPSR1HSP90AA1TDP1 | |
| SCHEMBL12657331 | 0.80 | MGLL (0.58) | MGLLFAAHNPSR1HSP90AA1TDP1 | |
| SCHEMBL7443516 | 0.77 | NR1H3 (0.59) | — | |
| SCHEMBL6749977 | 0.77 | AOC2 (0.59) | MGLLFAAHNPSR1HSP90AA1TDP1 | |
| SCHEMBL4194796 | 0.77 | CA2 (0.46) | ALDH1A1HPGDHTTLMNA | |
| SCHEMBL20495671 | 0.76 | MGLL (0.69) | MGLLFAAHNPSR1HSP90AA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6709679-B2 | CONSISTING OF NATIVE OR THIOLATED TRANSFERRIN OR ALBUMIN OR OF POLYETHYLENE GLYCOL WITH ATLEAST ONE MERCAPTAN, HYDROXY OR AMINE GROUP AND CYTOSTATIC COMPOUNDS DERIVED THROUGH MALEINIMIDE OR HYDROXYSUCCINIMIDE ESTER COMPOUNDS | KRATZ FELIX (DE) | 2004-03-23 | — | — | US | disclosed |
| US-20020019343-A1 | Antineoplastic conjugates of transferrin, albumin and polyethylene glycol | KRATZ FELIX (DE) | 2002-02-14 | — | — | US | disclosed |
| US-6310039-B1 | TUMOR-INHIBITING CONJUGATES OF PROTEINS AND POLYMERS CONSISTING OF A SUITABLE CARRIER SYSTEM AND CYTOSTATIC COMPOUNDS | KRATZ FELIX (DE) | 2001-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019343-A1 | Antineoplastic conjugates of transferrin, albumin and polyethylene glycol | TFRC, ALB, FOLR1 | MGLL 3432/4885FAAH 1010/4885NPSR1 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.