Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212205 | 0.74 | S100A4 (0.43) | ALDH1A1L3MBTL1TSHRTDP1GAA | |
| SCHEMBL19415422 | 0.71 | PARP1 (0.42) | PARP1ALDH1A1CD44 | |
| SCHEMBL29444072 | 0.70 | NOS3 (0.45) | PARP1ALDH1A1L3MBTL1HPGDTSHR | |
| SCHEMBL3630867 | 0.70 | NOS3 (0.45) | PARP1ALDH1A1L3MBTL1HPGDTSHR | |
| SCHEMBL2480404 | 0.68 | PARP1 (0.56) | PARP1ALDH1A1L3MBTL1CD44HSD17B10 | |
| SCHEMBL20364104 | 0.67 | ALDH1A1 (0.48) | PARP1ALDH1A1L3MBTL1CD44HSD17B10 | |
| SCHEMBL6751983 | 0.65 | PARP1 (0.44) | PARP1ALDH1A1L3MBTL1CD44HSD17B10 | |
| SCHEMBL2768935 | 0.65 | PARP1 (0.53) | PARP1ALDH1A1L3MBTL1HSD17B10TSHR | |
| SCHEMBL12657972 | 0.65 | PARP1 (0.44) | PARP1ALDH1A1L3MBTL1CD44HSD17B10 | |
| SCHEMBL192953 | 0.65 | CD44 (0.38) | PARP1ALDH1A1CD44HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706924-B2 | INCLUDES A STEP IN WHICH ORTHO-NITROTOLUENE IS REACTED WITH ONE OR MORE ACRYLIC ACID DERIVATIVES SUCH AS ACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | claimed |
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | claimed |
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | US | claimed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | claimed |
| US-6706924-B2 | INCLUDES A STEP IN WHICH ORTHO-NITROTOLUENE IS REACTED WITH ONE OR MORE ACRYLIC ACID DERIVATIVES SUCH AS ACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | US | disclosed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BBOX1, CYP4B1, NAT1 | PARP1 1388/4885ALDH1A1 455/4885L3MBTL1 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.