Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757242 | 0.83 | ADORA3 (0.42) | ADORA3ALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL6753935 | 0.78 | SCN10A (0.38) | ALDH1A1KDM4ESCN10A | |
| SCHEMBL6756285 | 0.78 | CBFB (0.38) | ADORA3ALDH1A1KDM4ESMN1; SMN2SCN10A | |
| SCHEMBL2950184 | 0.72 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6756139 | 0.72 | PARP1 (0.47) | ALDH1A1KDM4E | |
| SCHEMBL6756145 | 0.71 | PI4KA (0.44) | — | |
| SCHEMBL22962333 | 0.70 | AURKA (0.39) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6542923 | 0.70 | ADORA3 (0.43) | ADORA3ALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL6753957 | 0.70 | PI4KA (0.43) | KDM4E | |
| SCHEMBL6753880 | 0.70 | PI4KA (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |