Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614140 | 0.83 | MGAM (0.40) | CBFBALDH1A1 | |
| SCHEMBL6753933 | 0.78 | CBFB (0.42) | CBFBADAMTS5EGLN1SMN1; SMN2NPC1 | |
| SCHEMBL6756286 | 0.78 | ADORA3 (0.37) | ADORA3ALDH1A1SMN1; SMN2KDM4ESCN10A | |
| SCHEMBL6757190 | 0.74 | CBFB (0.46) | CBFBALDH1A1ADAMTS5EGLN1SMN1; SMN2 | |
| SCHEMBL2950184 | 0.72 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL6756137 | 0.72 | CBFB (0.42) | CBFBALDH1A1ADAMTS5OPRM1PARP1 | |
| SCHEMBL6756143 | 0.71 | CBFB (0.41) | CBFBOPRM1 | |
| SCHEMBL6753932 | 0.70 | GPR84 (0.42) | CBFBALDH1A1OPRM1 | |
| SCHEMBL6753984 | 0.70 | GPR84 (0.42) | CBFBALDH1A1OPRM1 | |
| SCHEMBL6753954 | 0.70 | GPR84 (0.42) | CBFBALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |