Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 5/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL6564869 | 1.00 | EPHX2 (0.46) | EPHX2HAO1FAAHCES2CES1 | |
| SCHEMBL2036114 | 0.97 | EPHX2 (0.49) | EPHX2HAO1FAAHCES2CES1 | |
| SCHEMBL9551953 | 0.97 | EPHX2 (0.49) | EPHX2HAO1FAAHCES2CES1 | |
| SCHEMBL9551951 | 0.97 | EPHX2 (0.49) | EPHX2HAO1FAAHCES2CES1 | |
| SCHEMBL9551957 | 0.95 | EPHX2 (0.47) | EPHX2HAO1FAAHCES2CES1 | |
| SCHEMBL143294 | 0.90 | EPHX2 (0.60) | EPHX2FAAHMAPTFABP3 | |
| SCHEMBL2043850 | 0.84 | EPHX2 (0.48) | EPHX2HAO1FAAHCES2CES1 | |
| SCHEMBL2047359 | 0.84 | EPHX2 (0.48) | EPHX2HAO1FAAHCES2CES1 | |
| SCHEMBL8376668 | 0.84 | EPHX2 (0.48) | EPHX2HAO1FAAHCES2CES1 | |
| SCHEMBL2042990 | 0.84 | EPHX2 (0.48) | EPHX2HAO1FAAHCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225214-B1 | Detergent composition | SHISEIDO CO LTD (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-0999260-B1 | Detergent composition | SHISEIDO CO LTD (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1225214-A2 | Detergent composition | SHISEIDO COMPANY LIMITED (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6303559-B1 | ALKALI METAL N-METHYLTAURATE SALT OF AN N-ACYLMETHYLTAURINE | SHISEIDO COMPANY, LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| EP-0999260-A2 | Detergent composition | SHISEIDO COMPANY LIMITED (JP) | 2000-05-10 | — | — | EP | disclosed |