SCHEMBL143294

SCHEMBL143294

CCCCCCCC/C=C\CCCCCCCC(=O)CNCCS(=O)(=O)[O-].[Na+]

nearest known ligand 0.60

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.60
FAAH O00519 4/20 0.54
FABP3 P05413 5/20 0.49
TERT O14746 2/20 0.46
GMNN O75496 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
APEX1 P27695 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
HSD17B10 Q99714 1/20 0.46
DUSP3 P51452 1/20 0.46
MMP2 P08253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2036114 0.93 EPHX2 (0.49) EPHX2FAAHFABP3MAPT
SCHEMBL9551951 0.93 EPHX2 (0.49) EPHX2FAAHFABP3MAPT
SCHEMBL9551953 0.93 EPHX2 (0.49) EPHX2FAAHFABP3MAPT
SCHEMBL9551957 0.92 EPHX2 (0.47) EPHX2FAAHFABP3MAPT
Potassium Ion SCHEMBL6564869 0.90 EPHX2 (0.46) EPHX2FAAHFABP3MAPT
Potassium Ion SCHEMBL6756334 0.90 EPHX2 (0.46) EPHX2FAAHFABP3MAPT
SCHEMBL1265735 0.86 EPHX2 (0.59) EPHX2FAAHTERTGMNNUSP2
SCHEMBL1265739 0.86 EPHX2 (0.59) EPHX2FAAHTERTGMNNUSP2
SCHEMBL28464305 0.86 FAAH (0.53) EPHX2FAAHFABP3TERTGMNN
SCHEMBL3623398 0.85 EPHX2 (0.58) EPHX2FAAHTERTGMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 843 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144252-A1 BROMINE- OR IODINE-PARA-SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND THEIR SALTS, AGENTS FOR PROTECTING USEFUL PLANTS OR CROP PLANTS COMPRISING THEM, METHODS FOR PRODUCING THEM AND THEIR USE AS SAFENERS BAYER AKTIENGESELLSCHAFT (DE) 2026-05-28 US disclosed
US-12617760-B2 [(5-phenyl-1-heteroaryl-1H-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants BAYER AKTIENGESELLSCHAFT (DE) 2026-05-05 US disclosed
US-12610950-B2 Method for weed control in lawn or turf DISCOVERY PURCHASER CORPORATION (US) 2026-04-28 US disclosed
US-12606542-B2 [(1,5-diheteroaryl-1H-1,2,4-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants BAYER AKTIENGESELLSCHAFT (DE) 2026-04-21 US disclosed
US-12583826-B2 [(1,5-diphenyl-1H-1,2,4-triazol-3-yl)oxy]acetic acid derivatives and salts thereof, crop protection compositions comprising them, methods for producing them and use thereof as safeners BAYER AKTIENGESELLSCHAFT (DE) 2026-03-24 US disclosed
US-12568972-B2 Pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2026-03-10 US disclosed
US-12509452-B2 Substituted-isoxazoline-containing aromatic compound, preparation method therefor, herbicidal composition and use thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2025-12-30 US disclosed
US-12509445-B2 Herbicidally active 4-cyclopropyl-6-[4-(trifluormethyl)pyrazol-1-yl)]pyrimidines BAYER AKTIENGESELLSCHAFT (DE) 2025-12-30 US disclosed
US-12497365-B2 4-pyridinyl formamide compound or derivative thereof, preparation method therefor, herbicidal composition and use thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2025-12-16 US disclosed
US-20250359550-A1 METHOD FOR WEED CONTROL IN LAWN OR TURF DISCOVERY PURCHASER CORPORATION (US) 2025-11-27 US disclosed
US-4963180-A Heterocyclic-substituted phenylsulfamates, and their use as herbicides and plant growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-16 US disclosed
US-4925478-A PLANT SAFENING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
US-4891057-A Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-02 US disclosed
US-4889864-A Carbamoylimidazole derivatives and their use as fungicides HOECHST AKTIENGESELLSCHAFT (DE) 1989-12-26 US disclosed
US-4870088-A ANIMALS AND PLANTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-26 US disclosed
US-4855309-A Pyridine derivatives, agents containing same, and the use thereof as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US disclosed
US-4808213-A 2,3,6-substituted phenylimidazole derivatives and the use thereof as growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-28 US disclosed
US-4786312-A PLANT GROWTH INHIBITION HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-22 US disclosed
US-4749403-A Herbicidal derivatives of imidazolidinone and imidazolidine thione HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-07 US disclosed
US-4495191-A Fungicidal 3-1,2,4-triazol-1-yl-1,2-diaryl-1-halogeno-prop-1-ene derivatives, compositions, and method of use HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497365-B2 4-pyridinyl formamide compound or derivative thereof, preparation method therefor, herbicidal composition and use thereof CYP4F8, CYP4F11, CYP4F12 EPHX2 1092/4885FAAH 699/4885FABP3 3417/4885
US-12617760-B2 [(5-phenyl-1-heteroaryl-1H-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants CBR3, CBR1, HACL2 EPHX2 2194/4885FAAH 318/4885FABP3 1109/4885
US-20260144252-A1 BROMINE- OR IODINE-PARA-SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND THEIR SALTS, AGENTS FOR PROTECTING USEFUL PLANTS OR CROP PLANTS COMPRISING THEM, METHODS FOR PRODUCING THEM AND THEIR USE AS SAFENERS CBR3, CBR1, CA3 EPHX2 2577/4885FAAH 571/4885FABP3 633/4885
US-12509452-B2 Substituted-isoxazoline-containing aromatic compound, preparation method therefor, herbicidal composition and use thereof CYP4X1, CBR3, CYP4B1 EPHX2 1672/4885FAAH 667/4885FABP3 2577/4885
US-12610950-B2 Method for weed control in lawn or turf GHDC, WASF2, CA3 EPHX2 2266/4885FAAH 3791/4885FABP3 1808/4885
US-20250359550-A1 METHOD FOR WEED CONTROL IN LAWN OR TURF NOTUM, WASF2, ASF1A EPHX2 1995/4885FAAH 3880/4885FABP3 3950/4885
US-12583826-B2 [(1,5-diphenyl-1H-1,2,4-triazol-3-yl)oxy]acetic acid derivatives and salts thereof, crop protection compositions comprising them, methods for producing them and use thereof as safeners CBR3, CBR1, HACL2 EPHX2 2437/4885FAAH 442/4885FABP3 903/4885
US-12509445-B2 Herbicidally active 4-cyclopropyl-6-[4-(trifluormethyl)pyrazol-1-yl)]pyrimidines CBR3, CBR1, HAX1 EPHX2 515/4885FAAH 619/4885FABP3 4290/4885
US-12568972-B2 Pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof CBR3, CHRM3, CYCS EPHX2 242/4885FAAH 925/4885FABP3 970/4885
US-12606542-B2 [(1,5-diheteroaryl-1H-1,2,4-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants CBR3, CBR1, HACL2 EPHX2 2087/4885FAAH 193/4885FABP3 979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.