Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756571 | 1.00 | CA2 (0.48) | CA2CAMK2ATRPV1ESR1ESR2 | |
| SCHEMBL7738555 | 0.85 | KEAP1 (0.63) | GPR52FFAR1MAPTKEAP1 | |
| SCHEMBL6758436 | 0.85 | KEAP1 (0.63) | GPR52FFAR1MAPTKEAP1 | |
| SCHEMBL6758432 | 0.85 | KEAP1 (0.63) | GPR52FFAR1MAPTKEAP1 | |
| SCHEMBL6759998 | 0.85 | KEAP1 (0.63) | GPR52FFAR1MAPTKEAP1 | |
| SCHEMBL7738550 | 0.85 | KEAP1 (0.63) | GPR52FFAR1MAPTKEAP1 | |
| SCHEMBL6761226 | 0.84 | FFAR1 (0.56) | GPR52FFAR1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL6761230 | 0.84 | FFAR1 (0.56) | GPR52FFAR1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL6759945 | 0.82 | FFAR1 (0.68) | GPR52FFAR1KEAP1 | |
| SCHEMBL6759953 | 0.82 | FFAR1 (0.68) | GPR52FFAR1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | LINDERMAN RUSSELL J (US) | 2004-02-19 | — | — | US | claimed |
| US-6660770-B2 | Inhibit digestion by terminating or blocking synthesis of digestive enzymes by activating trypsin modulating oostatic factor receptor | NORTH CAROLINA STATE UNIVERSITY | 2003-12-09 | — | — | US | claimed |
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | claimed |
| US-6521664-B1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2003-02-18 | — | — | US | claimed |
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2002-12-19 | — | — | US | claimed |
| WO-2002098220-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-12-12 | — | — | WO | claimed |
| EP-1241941-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | claimed |
| WO-2001041543-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-06-14 | — | — | WO | claimed |
| US-6720450-B2 | USING SUCH AS 7-CYCLOHEXYL-(4,5-METHANO)HEPTANOIC ACID; CONTROLLING BLOOD INGESTING INSECTS | NORTH CAROLINA STATE UNIVERSITY | 2004-04-13 | — | — | US | disclosed |
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | LINDERMAN RUSSELL J (US) | 2004-02-19 | — | — | US | disclosed |
| US-6660770-B2 | Inhibit digestion by terminating or blocking synthesis of digestive enzymes by activating trypsin modulating oostatic factor receptor | NORTH CAROLINA STATE UNIVERSITY | 2003-12-09 | — | — | US | disclosed |
| US-20030149103-A1 | Pesticidal activity of functionalized cyclopropanes | NORTH CAROLINA STATE UNIVERSITY | 2003-08-07 | — | — | US | disclosed |
| WO-2003051118-A1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED CYCLOPROPANES | NORTH CAROLINA STATE UNIVERSITY (US) | 2003-06-26 | — | — | WO | disclosed |
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | disclosed |
| US-6521664-B1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2003-02-18 | — | — | US | disclosed |
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2002-12-19 | — | — | US | disclosed |
| WO-2002098220-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-12-12 | — | — | WO | disclosed |
| EP-1241941-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001041543-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | VIP, ANPEP, APEH | CA2 1474/4885CAMK2A 3652/4885TRPV1 350/4885 |
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | VIP, ANPEP, APEH | CA2 1474/4885CAMK2A 3652/4885TRPV1 350/4885 |
| US-20030149103-A1 | Pesticidal activity of functionalized cyclopropanes | DDT, PPIF, CYP4F3 | CA2 1163/4885CAMK2A 2272/4885TRPV1 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.