Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 3/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630839 | 0.83 | IDO1 (0.45) | AKR1B1MAOBTOP1CES2CES1 | |
| SCHEMBL1515531 | 0.81 | FFAR1 (0.43) | SMN1; SMN2FFAR1 | |
| SCHEMBL531475 | 0.80 | MAOB (0.65) | AKR1B1MAOBTOP1PAMKEAP1 | |
| SCHEMBL531474 | 0.80 | MAOB (0.65) | AKR1B1MAOBTOP1PAMKEAP1 | |
| SCHEMBL17667746 | 0.79 | HSD11B1 (0.42) | AKR1B1MAOBTOP1KEAP1CES2 | |
| SCHEMBL1927794 | 0.79 | HDAC8 (0.57) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL6341882 | 0.79 | MAOB (0.41) | AKR1B1MAOBTOP1KEAP1CES2 | |
| SCHEMBL8594687 | 0.78 | TOP1 (0.58) | AKR1B1MAOBTOP1KEAP1CES2 | |
| SCHEMBL74275 | 0.77 | MAOB (0.67) | MAOBSMN1; SMN2CA1CA2ARG2 | |
| Allylbenzene SCHEMBL28153534 | 0.77 | AKR1B1 (0.45) | AKR1B1MAOBTOP1PAMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074387-B2 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AG (DE) | 2006-07-11 | — | — | US | claimed |
| US-20030202943-A1 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-30 | — | — | US | claimed |
| US-6565830-B1 | Contrast agent for imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | claimed |
| US-6287538-B1 | CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | claimed |
| US-5859214-A | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSHAFT (DE) | 1999-01-12 | — | — | US | claimed |
| US-5843399-A | DTPA monoamides for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | claimed |
| EP-0450742-B1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AG (DE) | 1994-07-06 | — | — | EP | claimed |
| WO-2023176458-A1 | DISINFECTING COMPOSITION CONTAINING THIAZOLE CARBOXYLIC ACID HYDRAZIDE COMPOUND | 石原産業株式会社 | 2023-09-21 | — | — | WO | disclosed |
| US-20110274651-A1 | Noscapine and Noscapine Analogs and Their Use in treating Infectious Diseases by Tubulin Binding Inhibition | EMORY UNIVERSITY (US) | 2011-11-10 | — | — | US | disclosed |
| EP-2328578-A2 | NOSCAPINE AND NOSCAPINE ANALOGS AND THEIR USE IN TREATING INFECTIOUS DISEASES BY TUBULIN BINDING INHIBITION | Emory University (US) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010030582-A2 | NOSCAPINE AND NOSCAPINE ANALOGS AND THEIR USE IN TREATING INFECTIOUS DISEASES BY TUBULIN BINDING INHIBITION | EMORY UNIVERSITY (US) | 2010-03-18 | — | — | WO | disclosed |
| EP-2042502-A1 | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2009-04-01 | — | — | EP | disclosed |
| EP-1544199-B1 | NITROGENOUS CONDENSED-RING COMPOUND AND USE THEREOF AS HIV INTEGRASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2008-10-15 | — | — | EP | disclosed |
| US-6355640-B1 | TREATMENT OF HYPERTENSION, UROGENITAL DISORDERS AND FORMED BY WITTIG REACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| US-6287538-B1 | CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-5859214-A | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSHAFT (DE) | 1999-01-12 | — | — | US | disclosed |
| US-5843399-A | DTPA monoamides for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| US-5773530-A | USEFUL AS PSYCHOSTIMULANTS, ANTIHYPERTENSIVE AGENTS AND REMEDIES FOR RENAL FAILURE, DIURETICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0737193-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018128-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030202943-A1 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SLC43A1, HRH4, ACSL6 | AKR1B1 986/4885MAOB 1117/4885TOP1 3737/4885 |
| US-20110274651-A1 | Noscapine and Noscapine Analogs and Their Use in treating Infectious Diseases by Tubulin Binding Inhibition | NOS1, NOS2, TBCA | AKR1B1 2676/4885MAOB 2046/4885TOP1 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.