Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545096 | 0.87 | LMNA (0.42) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL6757641 | 0.79 | LMNA (0.36) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL6757643 | 0.79 | LMNA (0.36) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL17804409 | 0.77 | TK1 (0.32) | ALDH1A1LMNAALBMAPK1TK1 | |
| SCHEMBL2038395 | 0.76 | ABL1 (0.45) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL2035886 | 0.75 | TK1 (0.53) | ALDH1A1LMNAALBMAPK1TK2 | |
| SCHEMBL9780986 | 0.75 | TK1 (0.53) | ALDH1A1LMNAALBMAPK1TK2 | |
| SCHEMBL23258398 | 0.75 | LMNA (0.43) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL5638638 | 0.74 | LMNA (0.42) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL1421772 | 0.74 | LMNA (0.42) | ALDH1A1LMNAALBMAPK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4841039-A | 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents | EMORY UNIVERSITY (US) | 1989-06-20 | — | — | US | disclosed |