Creatine

Creatine

SCHEMBL675799

CN(CC(=O)O)C(=N)N.[MgH2]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
CA1 P00915 13/20 0.39
CA2 P00918 13/20 0.39
EYA2 O00167 1/20 0.35
APP P05067 1/20 0.35
ACE P12821 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2C19 P33261 1/20 0.34
MVD P53602 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Creatine SCHEMBL20292685 0.98 NOS3 (0.43) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL30063981 0.98
Creatine SCHEMBL4007614 0.98 NOS3 (0.46) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL27979093 0.98 NOS3 (0.46) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL21567 0.98
Creatine SCHEMBL4269042 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL21810557 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL2774041 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL21404054 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2
Creatine SCHEMBL20497169 0.95 NOS3 (0.44) NOS3NOS1NOS2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240138438-A1 CREATINE NUTRITIONAL SUPPLEMENT MENTER DYLAN (US) 2024-05-02 US claimed
US-11865097-B2 Creatine nutritional supplement MENTER DYLAN (US) 2024-01-09 US claimed
CN-116606226-A Creatine magnesium and preparation method thereof 天津天鼎仁科技有限公司 2023-08-18 CN claimed
US-20230233499-A1 CREATINE NUTRITIONAL SUPPLEMENT MENTER DYLAN (US) 2023-07-27 US claimed
US-11642327-B2 Creatine nutritional supplement MENTER DYLAN ROBERT (US) 2023-05-09 US claimed
US-20230108723-A1 Multi-Nutrient Composition EXERKINE CORPORATION (CA) 2023-04-06 US claimed
US-11534458-B2 Phosphorus-sparing nutritional composition ALBION LABORATORIES, INC. (US) 2022-12-27 US claimed
US-11504413-B2 Multi-nutrient composition EXERKINE CORPORATION (CA) 2022-11-22 US claimed
US-20220054442-A1 Creatine Nutritional Supplement MENTER DYLAN (US) 2022-02-24 US claimed
US-11246846-B2 Trisodium citrate compositions having enhanced uptake across digestive mucosa TEMPESTA MICHAEL S (US) 2022-02-15 US claimed
US-20080089962-A1 NUTRITIONAL COMPOSITION FOR FACILITATING MUSCLE PUMPS MULTI FORMULATIONS LTD. (CA) 2008-04-17 US claimed
US-20080063689-A1 Dietary supplements containing anthocyanins and methods for using same to enhance creatine absorption and vasodilation FARBER MIKE 2008-03-13 US claimed
EP-1755401-A1 DIETARY SUPPLEMENTS CONTAINING EXTRACTS OF CINNAMON AND METHODS OF USING SAME TO ENHANCE CREATINE TRANSPORT MILLER, Peter (US) 2007-02-28 EP claimed
WO-2005099455-A1 DIETARY SUPPLEMENTS CONTAINING EXTRACTS OF CINNAMON AND METHODS OF USING SAME TO ENHANCE CREATINE TRANSPORT MILLER PETER (US) 2005-10-27 WO claimed
US-6903136-B2 Food supplements containing 4-hydroxyisoleucine and creatine EXPERIMENTAL AND APPLIED SCIENCES, INC. (US) 2005-06-07 US claimed
US-20040224035-A1 Dietary supplements containing extracts of cinnamon and methods of using same to enhance creatine transport IN INGREDIENTS, INC. 2004-11-11 US claimed
US-20040043013-A1 Metabolic uncoupling therapy MCCLEARY EDWARD LARRY (US) 2004-03-04 US claimed
US-20030224062-A1 Food supplements containing 4-hydroxyisoleucine and creatine NATIONAL SUPPLEMENT ASSOCIATION, INCORPORATED 2003-12-04 US claimed
WO-2003088947-A1 FOOD SUPPLEMENTS CONTAINING 4-HYDROXYISOLEUCINE AND CREATINE EXPERIMENTAL & APPLIED SCIENCES, INC. (US) 2003-10-30 WO claimed
US-6465018-B1 BLEND OF CREATINE, GINSENG, AND ASTRAGALUS, AND, OPTIONALLY, GLUTAMINE TUTTLE B DAVID (US) 2002-10-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080089962-A1 NUTRITIONAL COMPOSITION FOR FACILITATING MUSCLE PUMPS MUSK, BCAT1, PYGM NOS3 44/4885NOS1 38/4885NOS2 61/4885
US-11534458-B2 Phosphorus-sparing nutritional composition PHPT1, PPA1, PTH1R NOS3 2704/4885NOS1 2532/4885NOS2 3098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.