SCHEMBL497623

SCHEMBL497623

Cc1ccccc1OS(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
NOTUM Q6P988 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
ACHE P22303 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
LMNA P02545 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 1/20 0.37
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721153 1.00 TSHR (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL6759877 0.84 CA1 (0.35) TSHRKMT2ASMN1; SMN2KDM4ETDP1
SCHEMBL4136217 0.83 MAPT (0.47) MEN1KMT2ANPC1RAB9ACYP1A2
SCHEMBL29468562 0.82 TSHR (0.43) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL776589 0.82 TSHR (0.43) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL4121075 0.80 MRGPRX4 (0.35) TSHRMEN1KMT2AACHELMNA
SCHEMBL4127103 0.80 FABP4 (0.41) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL11609009 0.78 TSHR (0.41) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL4139110 0.77 TAS1R3 (0.33) KDM4ENOTUMNPSR1TDP1MAPT
SCHEMBL3884559 0.77 TSHR (0.39) TSHRMEN1KMT2ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3727313-A1 PROCESS FOR TREATING KERATIN FIBERS USING A HALOCHROMIC TRIARYLMETHANE DIRECT DYE, AN ALKALINE REVEALER AND THEN AN ACIDIC ERASER L'OREAL (FR) 2020-10-28 EP claimed
WO-2017109186-A1 METHOD FOR EXTRACTING METAL IONS FROM KERATINOUS FIBRES BY REPEATED APPLICATION OF AN ACID COMPOSITION L'OREAL (FR) 2017-06-29 WO claimed
EP-4731165-A1 COMPOSITE MATERIAL OF BISMUTH OXYCARBONATE AND POLYMERS FOR FILTERING ULTRAVIOLET RADIATION L'OREAL (FR) 2026-04-29 EP disclosed
EP-4712940-A1 COMPOSITION FOR CARING FOR THE KERATIN MATERIALS L'OREAL (FR) 2026-03-25 EP disclosed
US-12576015-B2 Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound, and cosmetic composition containing same L'OREAL (FR) 2026-03-17 US disclosed
US-12576016-B2 Composition containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one, a preservative and/or antioxidant, a surfactant and a polymer, and the method for processing keratin materials from the composition L'OREAL (FR) 2026-03-17 US disclosed
US-12521333-B2 Composition comprising compound of thiopyridinone type and polyglyceryl-based emulsifiers L'OREAL (FR) 2026-01-13 US disclosed
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER OREAL (FR) 2025-12-18 US disclosed
US-20250381115-A1 STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME OREAL (FR) 2025-12-18 US disclosed
US-20250381116-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME OREAL (FR) 2025-12-18 US disclosed
US-20250375367-A1 STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME OREAL (FR) 2025-12-11 US disclosed
WO-2009034059-A2 AZO QUINOLINIUM COMPOUNDS COMPRISING A DISULPHIDE/THIOL UNIT, COMPOSITIONS CONTAINING SAME, PROCESS FOR DYEING KERATIN FIBRES AND DEVICE L'OREAL (FR) 2009-03-19 WO disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
EP-1148570-B1 Nonaqueous electrolyte secondary battery SONY CORP (JP) 2006-06-07 EP disclosed
US-20050208385-A1 Negative electrode active material capable of being doped/undoped with lithium, and a nonaqueous electrolyte of thiols, thiophenes, thioanisoles, thiazoles, thioacetates, aromatic sulfones; longer cycle life NIRASAWA TAKAO 2005-09-22 US disclosed
US-6913856-B2 Sulfur compound as nonaqueous electrolyte SONY CORPORATION (JP) 2005-07-05 US disclosed
US-20020018940-A1 Sulfur compound as nonaqueous electrolyte SONY CORPORATION (JP) 2002-02-14 US disclosed
EP-1148570-A2 Nonaqueous electrolyte secondary battery SONY CORPORATION (JP) 2001-10-24 EP disclosed
US-5789054-A Spin-transition parent compounds and devices having means for writing, storing and erasing, which comprise an active medium including at least one of said compounds U.S. PHILIPS CORPORATION (US) 1998-08-04 US disclosed
EP-0745986-A1 Spin-transition chemical starting compounds and devices provided with writing, memorizing and erasing means comprising an active medium that contains at least one of these compounds LABORATOIRES D'ELECTRONIQUE PHILIPS S.A.S. (FR) 1996-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375367-A1 STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME TPMT, CRY1, TDP1 TSHR 3430/4885MEN1 385/4885KMT2A 399/4885
US-12576015-B2 Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound, and cosmetic composition containing same EBP, CUTA, HAO2 TSHR 3619/4885MEN1 2722/4885KMT2A 4349/4885
US-20250381115-A1 STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME TPMT, TPR, TYMP TSHR 2271/4885MEN1 173/4885KMT2A 683/4885
US-12576016-B2 Composition containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one, a preservative and/or antioxidant, a surfactant and a polymer, and the method for processing keratin materials from the composition KRT18, BAK1, GPX4 TSHR 4857/4885MEN1 3582/4885KMT2A 2273/4885
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER H1-0, PARN, FASN TSHR 1030/4885MEN1 688/4885KMT2A 2388/4885
US-20250381116-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME TBCB, CCNB3, CYP24A1 TSHR 2123/4885MEN1 1459/4885KMT2A 3398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.