SCHEMBL6760087

SCHEMBL6760087

Cn1cc(OCc2ccccc2)oc1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 4/20 0.44
MAOB P27338 5/20 0.42
MAOA P21397 4/20 0.42
NPC1 O15118 3/20 0.42
CA9 Q16790 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
MTNR1A P48039 1/20 0.42
CA14 Q9ULX7 1/20 0.42
FAAH O00519 2/20 0.41
MGLL Q99685 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757710 0.79 MAPK14 (0.49) NPC1MEN1KMT2AFAAHMGLL
SCHEMBL6762431 0.77 MET (0.43) PKMMAOBCA9MEN1KMT2A
SCHEMBL6760443 0.76 GAA (0.41) PKMMAOBMAOANPC1CA9
SCHEMBL25065572 0.71 CYP1A1 (0.42) PKMMAOBLMNAACHEBCHE
SCHEMBL6759650 0.69 HPGD (0.47) MEN1KMT2AACHEBCHELIPC
SCHEMBL16791957 0.68 PTPN1 (0.46) PKMKDM4CL3MBTL1RAB9ASMN1; SMN2
SCHEMBL5297735 0.68 MAPK14 (0.66) MAOBL3MBTL1
SCHEMBL4680991 0.68 HPGD (0.49) MEN1KMT2AFAAHMGLLSMN1; SMN2
SCHEMBL6765408 0.68 PKM (0.49) PKMMAOBMAOANPC1FAAH
SCHEMBL6761320 0.67 HPGD (0.44) MEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 PKM 2042/4885MAOB 1564/4885MAOA 1120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.