SCHEMBL6765408

SCHEMBL6765408

Cn1c(OCc2ccccc2)noc1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.49
MAOA P21397 2/20 0.49
MAOB P27338 2/20 0.49
BRD4 O60885 2/20 0.47
CYP1A2 P05177 7/20 0.44
ALDH1A1 P00352 4/20 0.44
TSHR P16473 3/20 0.44
CLK4 Q9HAZ1 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP2C19 P33261 4/20 0.41
CYP3A4 P08684 3/20 0.41
FAAH O00519 2/20 0.41
MGLL Q99685 2/20 0.41
LMNA P02545 2/20 0.41
GAA P10253 1/20 0.41
CYP2C9 P11712 3/20 0.40
CASP1 P29466 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6771552 0.78 ALDH1A1 (0.44) PKMMAOAMAOBBRD4CYP1A2
SCHEMBL6766066 0.75 ALDH1A1 (0.47) BRD4CYP1A2ALDH1A1NPC1RAB9A
SCHEMBL14505636 0.73 PKM (0.58) PKMMAOAMAOBBRD4CYP1A2
SCHEMBL29351898 0.72 BACE1 (0.47) CYP1A2ALDH1A1TSHRNPC1RAB9A
SCHEMBL20793061 0.71 MAOB (0.63) PKMMAOAMAOBCYP1A2ALDH1A1
SCHEMBL21028576 0.70 MAOA (0.55) PKMMAOAMAOBCYP1A2ALDH1A1
SCHEMBL3525163 0.69 PKM (0.50) PKMMAOAMAOBCYP1A2ALDH1A1
SCHEMBL16382563 0.68 BRD4 (0.50) PKMMAOAMAOBBRD4CYP1A2
SCHEMBL3521025 0.68 MAOB (0.49) PKMMAOAMAOBCYP1A2ALDH1A1
SCHEMBL6760087 0.68 PKM (0.44) PKMMAOAMAOBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063581-A1 Herbicidal oxadiazolidines THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-01 US disclosed
EP-1147096-A1 HERBICIDAL OXADIAZOLIDINES E. I. du Pont de Nemours and Company (US) 2001-10-24 EP disclosed
WO-2000043377-A1 HERBICIDAL OXADIAZOLIDINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063581-A1 Herbicidal oxadiazolidines XDH, CBR3, CYP4X1 PKM 2825/4885MAOA 341/4885MAOB 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.