SCHEMBL6760099

SCHEMBL6760099

O=c1oc(Oc2ccccc2)cn1C(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
FAAH O00519 4/20 0.37
MGLL Q99685 4/20 0.36
CYP19A1 P11511 3/20 0.35
IDH1 O75874 1/20 0.35
GSTP1 P09211 1/20 0.34
LTA4H P09960 1/20 0.33
TSHR P16473 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
OPRL1 P41146 1/20 0.33
SRD5A2 P31213 1/20 0.33
USP2 O75604 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
PTGS1 P23219 1/20 0.33
NTRK1 P04629 1/20 0.33
IGF1R P08069 1/20 0.33
FGFR1 P11362 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4680402 0.85 FAAH (0.46) FAAHMGLLPTGS1
SCHEMBL4681001 0.83 FAAH (0.42) GAAFAAHMGLLCYP19A1CYP3A4
SCHEMBL6759635 0.80 GAA (0.40) GAAFAAHTSHRUSP2CYP3A4
SCHEMBL6761258 0.79 GAA (0.39) GAAFAAHMGLLCYP19A1TSHR
SCHEMBL6760443 0.78 GAA (0.41) GAAFAAHMGLLIDH1GSTP1
SCHEMBL6764059 0.73 ALDH1A1 (0.41) FAAHMGLLCYP19A1
SCHEMBL4679478 0.69 FAAH (0.51) FAAHMGLL
SCHEMBL4676274 0.69 FAAH (0.51) FAAHMGLL
SCHEMBL4678109 0.68 FAAH (0.43) FAAHMGLL
SCHEMBL4678103 0.68 FAAH (0.43) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 GAA 2791/4885FAAH 183/4885MGLL 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.