SCHEMBL6760449

SCHEMBL6760449

COc1ccc(CC2CCCS2)cc1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ALOX12 P18054 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
HRH3 Q9Y5N1 2/20 0.40
IDO1 P14902 1/20 0.40
EPHX2 P34913 1/20 0.40
ALDH1A1 P00352 1/20 0.39
SIGMAR1 Q99720 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7262319 0.81 MAPT (0.38) LMNASMN1; SMN2HRH3IDO1
SCHEMBL8998 0.77 FAAH (0.43)
SCHEMBL3365060 0.73 LTA4H (0.51) HRH3IDO1EPHX2
SCHEMBL3367622 0.73 LTA4H (0.48) IDO1SIGMAR1
SCHEMBL622656 0.72 IDO1 (0.50) SMN1; SMN2IDO1
SCHEMBL6628369 0.72 LTA4H (0.54) SMN1; SMN2HRH3EPHX2
SCHEMBL28090 0.72 POLB (0.44)
Ammonia Solution, Strong SCHEMBL8172708 0.71 IDO1 (0.48) SMN1; SMN2IDO1
SCHEMBL9359327 0.70 MAOA (0.58) ALDH1A1
SCHEMBL11503831 0.70 EPHX2 (0.43) SMN1; SMN2HRH3IDO1EPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6703190-B2 Method for producing resist structures INFINEON TECHNOLOGIES AG (DE) 2004-03-09 US disclosed
US-20030008240-A1 Method for producing resist structures POLARIS INNOVATIONS LIMITED (IE) 2003-01-09 US disclosed