Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21721700 | 0.84 | KDM4E (0.36) | TGFBR1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27719767 | 0.81 | MPO (0.40) | L3MBTL1KDM4EALDH1A1PDE4BTP53 | |
| SCHEMBL29398775 | 0.80 | TGFBR1 (0.47) | TGFBR1L3MBTL1KDM4EALDH1A1TP53 | |
| SCHEMBL3276395 | 0.80 | TGFBR1 (0.40) | TGFBR1L3MBTL1KDM4EALDH1A1TP53 | |
| SCHEMBL15056138 | 0.79 | TGFBR1 (0.39) | TGFBR1L3MBTL1TP53LMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL33526345 | 0.79 | L3MBTL1 (0.40) | TGFBR1L3MBTL1KDM4EALDH1A1PDE4B | |
| SCHEMBL13169985 | 0.79 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1PDE4BTP53 | |
| SCHEMBL1460054 | 0.78 | TGFBR1 (0.39) | TGFBR1L3MBTL1KDM4EALDH1A1TP53 | |
| SCHEMBL8932284 | 0.77 | TGFBR1 (0.41) | TGFBR1L3MBTL1KDM4EALDH1A1PTGS1 | |
| SCHEMBL17066901 | 0.76 | MPO (0.42) | TGFBR1L3MBTL1KDM4EALDH1A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183351-B2 | Avermectin derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-22 | — | — | US | disclosed |
| US-8183351-B2 | Avermectin derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-22 | — | — | US | disclosed |
| US-20100234312-A1 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100234312-A1 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | US | disclosed |
| EP-0789698-B1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 1999-07-07 | — | — | EP | disclosed |
| US-5763359-A | N-(1-ethyl-4-pyrazolyl)triazoloazinesulfonamide herbicides | DOW AGROSCIENCES LLC (US) | 1998-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234312-A1 | AVERMECTIN DERIVATIVES | OXTR, C3AR1, CBR3 | TGFBR1 442/4885L3MBTL1 64/4885KDM4E 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.