Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 13/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.43 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28494246 | 0.67 | MAOA (0.61) | ALDH1A1CA2LMNARAB9ASLC6A3 | |
| SCHEMBL6768350 | 0.67 | KMT2A (0.47) | ALDH1A1CES2LOXMAOBCA2 | |
| SCHEMBL6766023 | 0.67 | CA2 (0.50) | ALDH1A1GFERMAOBCA2LMNA | |
| SCHEMBL8930590 | 0.65 | CES2 (0.65) | ALDH1A1GFERCES2LOXLOXL3 | |
| SCHEMBL30641875 | 0.65 | ALDH1A1 (1.00) | ALDH1A1GFERCES2LOXLOXL3 | |
| SCHEMBL6773284 | 0.65 | SMN1; SMN2 (0.44) | ALDH1A1GFERCES2LOXLOXL3 | |
| SCHEMBL30641876 | 0.62 | ALDH1A1 (0.67) | ALDH1A1GFERCES2LOXLOXL3 | |
| SCHEMBL17290527 | 0.62 | CES2 (0.57) | CES2LOXLOXL3LOXL4LOXL2 | |
| SCHEMBL17454853 | 0.62 | MAOB (0.48) | ALDH1A1MAOBRAB9A | |
| SCHEMBL28185949 | 0.62 | MAOB (0.48) | ALDH1A1MAOBHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825192-B1 | NON-N-METHYL-D-ASPARTATE (NON- NMDA) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTIC ACTION, FOR EXAMPLE 2-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC ACID (AMPA) RECEPTOR ANTAGONISTIC ACTION | EISAI CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |