Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | USP1 | O94782 | 1/20 | 0.37 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212810 | 0.70 | CA2 (0.50) | CA2RAB9ASLC6A3ALDH1A1KMT2A | |
| Pemoline Dione SCHEMBL7864463 | 0.67 | CA2 (1.00) | CA2RAB9ASLC6A3ALDH1A1KMT2A | |
| SCHEMBL6763545 | 0.67 | ALDH1A1 (0.48) | CA2RAB9ASLC6A3ALDH1A1GFER | |
| Pemoline Dione SCHEMBL11265294 | 0.66 | CA2 (0.96) | CA2RAB9ASLC6A3ALDH1A1KMT2A | |
| SCHEMBL31650964 | 0.65 | ALDH1A1 (0.56) | CA2RAB9ASLC6A3ALDH1A1KMT2A | |
| SCHEMBL8181404 | 0.65 | CA2 (0.67) | CA2RAB9ASLC6A3ALDH1A1KMT2A | |
| Pemoline SCHEMBL558128 | 0.65 | CA2 (0.67) | CA2RAB9ASLC6A3ALDH1A1KMT2A | |
| SCHEMBL28577740 | 0.64 | ALDH1A1 (0.43) | CA2RAB9ASLC6A3ALDH1A1KMT2A | |
| SCHEMBL30991581 | 0.64 | CA2 (0.54) | CA2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28790257 | 0.63 | CA2 (0.50) | CA2RAB9ASLC6A3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825192-B1 | NON-N-METHYL-D-ASPARTATE (NON- NMDA) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTIC ACTION, FOR EXAMPLE 2-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC ACID (AMPA) RECEPTOR ANTAGONISTIC ACTION | EISAI CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |