Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Inosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.59 |
| ▸ | DOT1L | Q8TEK3 | 10/20 | 0.53 |
| ▸ | NSD2 | O96028 | 3/20 | 0.53 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.53 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.53 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.53 |
| ▸ | INMT | O95050 | 2/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.53 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.53 |
| ▸ | RNMT | O43148 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.53 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.53 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.53 |
| ▸ | FASN | P49327 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Inosine SCHEMBL27610579 | 1.00 | NNMT (0.59) | NNMTDOT1LNSD2SETD7PRMT1 | |
| Arginine SCHEMBL5784577 | 0.89 | EZH2 (0.59) | NNMTEZH2 | |
| SCHEMBL6764072 | 0.88 | MARS1 (0.59) | NNMTDOT1LNSD2SETD7PRMT1 | |
| SCHEMBL6764075 | 0.88 | MARS1 (0.59) | NNMTDOT1LNSD2SETD7PRMT1 | |
| Guanosine SCHEMBL28986666 | 0.83 | HINT1 (0.54) | NNMT | |
| Adenosine SCHEMBL8013455 | 0.81 | NNMT (0.70) | NNMTDOT1LNSD2SETD7PRMT1 | |
| Adenosine SCHEMBL8013453 | 0.81 | NNMT (0.70) | NNMTDOT1LNSD2SETD7PRMT1 | |
| Adenosine Phosphate SCHEMBL15670455 | 0.81 | EZH2 (0.70) | NNMTDOT1LNSD2SETD7PRMT1 | |
| Adenosine Phosphate SCHEMBL18730264 | 0.81 | EZH2 (0.70) | NNMTDOT1LNSD2SETD7PRMT1 | |
| SCHEMBL30208502 | 0.79 | SLC29A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040192553-A1 | Inosine L-Arginine salt and uses thereof | AJINOMOTO CO., INC. (JP) | 2004-09-30 | — | — | US | disclosed |
| JP-2003096090-A | INOSINE L-ARGININE SALT AND ITS APPLICATION | AJINOMOTO CO INC | 2003-04-03 | — | — | JP | disclosed |