Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.37 |
| ▸ | CTSL | P07711 | 9/20 | 0.37 |
| ▸ | CTSS | P25774 | 9/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 2/20 | 0.34 |
| ▸ | RPLP1 | P05386 | 2/20 | 0.34 |
| ▸ | RPLP0 | P05388 | 2/20 | 0.34 |
| ▸ | RPS17 | P08708 | 2/20 | 0.34 |
| ▸ | RPSA | P08865 | 2/20 | 0.34 |
| ▸ | RPS2 | P15880 | 2/20 | 0.34 |
| ▸ | RPL35A | P18077 | 2/20 | 0.34 |
| ▸ | RPL7 | P18124 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971691 | 0.89 | MAPK1 (0.36) | CTSKCTSLCTSSSMN1; SMN2MAPK1 | |
| SCHEMBL7534924 | 0.88 | CTSK (0.42) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6214152 | 0.86 | CTSK (0.37) | CTSKCTSLCTSSSMN1; SMN2MAPK1 | |
| SCHEMBL7428041 | 0.86 | CTSK (0.41) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL7435423 | 0.86 | CTSK (0.39) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6764532 | 0.86 | CTSK (0.33) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7431508 | 0.85 | MC4R (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7538204 | 0.81 | TAS1R3 (0.49) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5971129 | 0.80 | REN (0.41) | CTSKCTSLCTSSMAPK1KMT2A | |
| SCHEMBL6591072 | 0.80 | PTGDR2 (0.33) | RPLP1RPLP0RPS17RPSARPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034157-A9 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-05-10 | — | — | WO | disclosed |