Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13971145 | 1.00 | — | — | |
| SCHEMBL345042 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL15577381 | 0.97 | ALDH1A1 (0.50) | ALDH1A1OPRM1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL6264548 | 0.97 | ALDH1A1 (0.50) | ALDH1A1OPRM1S1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL27483388 | 0.97 | ALDH1A1 (0.50) | ALDH1A1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL272998 | 0.94 | OPRM1 (0.50) | ALDH1A1OPRM1S1PR2S1PR1S1PR3 | |
| SCHEMBL1298154 | 0.91 | OPRM1 (0.57) | ALDH1A1OPRM1S1PR2S1PR1S1PR3 | |
| Fluoride SCHEMBL1995827 | 0.90 | OPRM1 (0.48) | ALDH1A1OPRM1S1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL1993996 | 0.90 | OPRM1 (0.48) | ALDH1A1OPRM1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL1997517 | 0.90 | OPRM1 (0.48) | ALDH1A1OPRM1S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167080-A1 | Glucopyranoside benzothiophenes | DODGE JEFFREY A (US) | 2004-08-26 | — | — | US | disclosed |
| US-6723739-B1 | INHIBITING POSTMENOPAUSAL OSTEOPOROSIS | ELI LILLY AND COMPANY | 2004-04-20 | — | — | US | disclosed |
| EP-0683170-B1 | Glucopyranoside benzothiophenes | LILLY CO ELI (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5567820-A | THERAPY FOR BONE DISEASES | ELI LILLY AND COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0683170-A1 | Glucopyranoside benzothiophenes | ELI LILLY AND COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167080-A1 | Glucopyranoside benzothiophenes | UGGT1, SLC5A1, B4GALT1 | ALDH1A1 378/4885OPRM1 3420/4885S1PR2 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.