Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL6765039

Cc1ccc([S+](c2ccccc2)c2ccccc2)cc1C.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GPR3 P46089 2/20 0.40
PTPN1 P18031 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KCNH2 Q12809 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 1/20 0.33
TAS2R14 Q9NYV8 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CTSG P08311 1/20 0.32
CMA1 P23946 1/20 0.32
PKM P14618 1/20 0.32
PKLR P30613 1/20 0.32
HTT P42858 1/20 0.32
NSD2 O96028 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL6118365 0.85 GPR3 (0.48) GPR3PTPN1KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL36147 0.84 GPR3 (0.47) TDP1GPR3PTPN1ALDH1A1L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL1088679 0.84 GPR3 (0.47) TDP1GPR3PTPN1ALDH1A1L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL31155703 0.83 GPR3 (0.50) GPR3PTPN1ALDH1A1KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL37032 0.83 GPR3 (0.50) GPR3PTPN1ALDH1A1KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL1615717 0.83 GPR3 (0.47) GPR3PTPN1L3MBTL1KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL10008137 0.82 GPR3 (0.48) GPR3PTPN1KCNH2ACHE
SCHEMBL3200037 0.82 CES2 (0.39) LMNATDP1ALDH1A1MAPTCES2
SCHEMBL3191969 0.82 CES2 (0.39) LMNATDP1ALDH1A1MAPTCES2
Trifluoromethanesulfonic Acid SCHEMBL3140872 0.81 ACHE (0.39) GPR3PTPN1KCNH2SMN1; SMN2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1113005-B1 Sulfonium salt compounds WAKO PURE CHEM IND LTD (JP) 2003-08-06 EP disclosed
EP-1238969-A2 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2002-09-11 EP disclosed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP disclosed