SCHEMBL6765299

SCHEMBL6765299

O=C(NO)Nc1ccc(Cl)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.59
MAPT P10636 5/20 0.55
KDM4E B2RXH2 3/20 0.55
KMT2A Q03164 2/20 0.55
HTT P42858 1/20 0.55
POLB P06746 1/20 0.55
MEN1 O00255 1/20 0.55
NPC1 O15118 4/20 0.54
EGFR P00533 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TRPV1 Q8NER1 1/20 0.52
PYGL P06737 1/20 0.52
ALDH1A1 P00352 1/20 0.51
PDK1 Q15118 1/20 0.51
PDK2 Q15119 1/20 0.51
PDK3 Q15120 1/20 0.51
PDK4 Q16654 1/20 0.51
USP2 O75604 1/20 0.51
HPGD P15428 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5471126 0.90 RAB9A (0.65) RAB9AMAPTKDM4EKMT2AHTT
SCHEMBL9035650 0.83 RAB9A (0.58) RAB9AMAPTKDM4EKMT2AHTT
SCHEMBL5867147 0.83 RAB9A (0.58) RAB9AMAPTKDM4EKMT2AHTT
SCHEMBL12919798 0.82 RAB9A (0.56) RAB9AMAPTKDM4ENPC1EGFR
SCHEMBL31206286 0.81 ALDH1A1 (0.70) RAB9AMAPTKDM4EKMT2AHTT
SCHEMBL31206327 0.81 MAPT (0.66) RAB9AMAPTKDM4EKMT2AHTT
SCHEMBL21858368 0.81 ALDH1A1 (0.70) RAB9AMAPTKDM4EKMT2AHTT
SCHEMBL4548129 0.81 MAPT (0.66) RAB9AMAPTKDM4EKMT2AHTT
Hydrochloric Acid SCHEMBL9004742 0.81 RAB9A (0.56) RAB9AMAPTKDM4EKMT2AHTT
SCHEMBL9834106 0.80 RAB9A (0.57) RAB9AKDM4ENPC1EGFRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063581-A1 Herbicidal oxadiazolidines THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063581-A1 Herbicidal oxadiazolidines XDH, CBR3, CYP4X1 RAB9A 1818/4885MAPT 4785/4885KDM4E 2510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.