Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838791 | 1.00 | CTSK (0.46) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL4765437 | 0.93 | TRPV4 (0.46) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL4765434 | 0.93 | TRPV4 (0.46) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL4765345 | 0.90 | CTSK (0.46) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL4765349 | 0.90 | CTSK (0.46) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL6771256 | 0.89 | CTSK (0.50) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL6592507 | 0.89 | TRPV4 (0.45) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL6592504 | 0.89 | TRPV4 (0.45) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL4762325 | 0.88 | CTSK (0.47) | CTSKTAS1R3TAS1R1UTS2RTRPV4 | |
| SCHEMBL4768869 | 0.88 | TAS1R3 (0.47) | CTSKTAS1R3TAS1R1UTS2RTRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002487-A1 | Protease inhibitors | MARQUIS ROBERT WELLS (US) | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002487-A1 | Protease inhibitors | CTSK, MMP13, CTSZ | CTSK 1/4885TAS1R3 2506/4885TAS1R1 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.