Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769465 | 0.89 | ALDH1A1 (0.36) | DHODHALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL6165346 | 0.89 | ALDH1A1 (0.40) | DHODHALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL6770489 | 0.88 | DHODH (0.35) | DHODH | |
| SCHEMBL6771481 | 0.82 | OPRM1 (0.43) | DHODHALDH1A1KMT2APPARA | |
| SCHEMBL6771327 | 0.82 | DHODH (0.32) | DHODH | |
| SCHEMBL6770490 | 0.82 | ALDH1A1 (0.42) | DHODHALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL6769804 | 0.81 | PPARA (0.38) | DHODHPDE4BPPARA | |
| SCHEMBL6776388 | 0.81 | OPRM1 (0.38) | DHODH | |
| SCHEMBL6766574 | 0.80 | ALDH1A1 (0.39) | DHODHALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL6777392 | 0.80 | DHODH (0.36) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |