Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769850 | 0.88 | OPRM1 (0.38) | OPRM1DHODH | |
| SCHEMBL6168419 | 0.88 | DHODH (0.42) | OPRM1DHODHBUB1 | |
| SCHEMBL6771481 | 0.85 | OPRM1 (0.43) | OPRM1DHODHBUB1 | |
| SCHEMBL6769804 | 0.84 | PPARA (0.38) | OPRM1DHODHBUB1 | |
| SCHEMBL6772503 | 0.84 | OPRM1 (0.40) | OPRM1BUB1SRC | |
| SCHEMBL6777392 | 0.82 | DHODH (0.36) | DHODHBUB1 | |
| SCHEMBL6770489 | 0.81 | DHODH (0.35) | DHODHBUB1 | |
| SCHEMBL6767248 | 0.81 | DHODH (0.35) | DHODH | |
| SCHEMBL6770751 | 0.81 | OPRM1 (0.45) | OPRM1DHODHSRC | |
| SCHEMBL6770575 | 0.79 | GPBAR1 (0.39) | OPRM1DHODHSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |