SCHEMBL6767771

SCHEMBL6767771

ON1c2ccccc2Sc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.58
BCHE P06276 13/20 0.58
ACHE P22303 4/20 0.54
NOX1 Q9Y5S8 1/20 0.54
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21449139 0.82 BCHE (0.57) BCHEACHEMEN1LMNAKMT2A
SCHEMBL3794995 0.78 NOX1 (0.44) MAOABCHEACHENOX1PTGS1
SCHEMBL1718054 0.78 MAOA (0.64) MAOABCHEACHENOX1PTGS1
SCHEMBL17265909 0.77 MEN1 (0.43) MAOABCHEACHENOX1MEN1
SCHEMBL21082763 0.76 TLR9 (0.43) BCHEPTGS1LMNA
SCHEMBL3797588 0.74 NOX1 (0.45) MAOABCHEACHENOX1PTGS1
SCHEMBL18932210 0.74 MAOA (0.58) MAOABCHEACHENOX1PTGS1
SCHEMBL3235747 0.74 MAOA (0.58) MAOABCHEACHENOX1PTGS1
SCHEMBL8038574 0.74 MAOA (0.58) MAOABCHEACHENOX1PTGS1
SCHEMBL12655447 0.74 MAOA (0.58) MAOABCHEACHENOX1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS THE SCRIPPS RESEARCH INSTITUTE 2020-10-08 US disclosed
US-20180212158-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-07-26 US disclosed
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-08-24 US disclosed
WO-2017011531-A2 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-01-19 WO disclosed
WO-2015175678-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-11-19 WO disclosed
WO-2015059071-A1 RESIN MIXTURE BASED ON A VINYL ESTER URETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF HILTI AKTIENGESELLSCHAFT (LI) 2015-04-30 WO disclosed
EP-2862899-A1 Resin mixture based on a vinyl ester urethane resin, method for its preparation and use HILTI Aktiengesellschaft (LI) 2015-04-22 EP disclosed
CN-1541202-A Stabilization of ethylenically unsaturated compounds with amidoximes 巴斯福股份公司 2004-10-27 CN disclosed
US-20040210078-A1 Satbilisation of ethylenically-unsaturated compounds with amidoximes SUTORIS HEINZ FRIEDRICH 2004-10-21 US disclosed
EP-1419141-A1 STABILISATION OF ETHYLENICALLY-UNSATURATED COMPOUNDS WITH AMIDOXIMES BASF Aktiengesellschaft (DE) 2004-05-19 EP disclosed
WO-2003016268-A1 STABILISATION OF ETHYLENICALLY-UNSATURATED COMPOUNDS WITH AMIDOXIMES BASF AKTIENGESELLSCHAFT (DE) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS ALDH1A2, DDT, CLTB MAOA 228/4885BCHE 1923/4885ACHE 914/4885
US-20180212158-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS MSN, DDT, NECTIN4 MAOA 175/4885BCHE 1587/4885ACHE 1237/4885
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS CYBA, DDT, DRD1 MAOA 142/4885BCHE 2000/4885ACHE 1264/4885
US-20040210078-A1 Satbilisation of ethylenically-unsaturated compounds with amidoximes PNMT, NIT2, NNMT MAOA 489/4885BCHE 1444/4885ACHE 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.