Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771355 | 0.94 | POLB (0.47) | NPC1RAB9AALDH1A1MAPTTSHR | |
| SCHEMBL6773275 | 0.89 | TRPV1 (0.43) | HDAC3HDAC1 | |
| SCHEMBL6779684 | 0.89 | MCHR1 (0.50) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6774104 | 0.88 | POLB (0.44) | NPC1RAB9AKMT2APOLBMEN1 | |
| SCHEMBL6768556 | 0.87 | SMN1; SMN2 (0.49) | NPC1RAB9AALDH1A1MAPTTSHR | |
| SCHEMBL6772992 | 0.86 | HDAC3 (0.40) | ALDH1A1MAPTSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL6779944 | 0.85 | HDAC3 (0.48) | HDAC3HDAC1 | |
| SCHEMBL6773853 | 0.85 | NOS3 (0.46) | ALDH1A1HPGDPOLBHDAC3HDAC1 | |
| SCHEMBL6768729 | 0.85 | TLR7 (0.47) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6773965 | 0.83 | BRD4 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |