Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773253 | 0.94 | GAA (0.41) | POLBTP53GAAHTTABL1 | |
| SCHEMBL6772992 | 0.90 | HDAC3 (0.40) | TP53TLR7GAAHTTHDAC3 | |
| SCHEMBL6768544 | 0.88 | NPC1 (0.49) | POLBTP53MEN1KMT2ANPC1 | |
| SCHEMBL6773853 | 0.87 | NOS3 (0.46) | POLBTLR7GAAHDAC3HDAC1 | |
| SCHEMBL6773275 | 0.87 | TRPV1 (0.43) | TLR7HDAC3HDAC1 | |
| SCHEMBL6778937 | 0.86 | TLR7 (0.42) | POLBTP53TLR7GAAMEN1 | |
| SCHEMBL6773965 | 0.85 | BRD4 (0.44) | TLR7MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6779944 | 0.85 | HDAC3 (0.48) | HDAC3HDAC1 | |
| SCHEMBL6773364 | 0.84 | RXFP1 (0.43) | POLBTP53TLR7GAANPC1 | |
| SCHEMBL6774657 | 0.83 | MAPT (0.49) | POLBTP53TLR7GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |