Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | DRD4 | P21917 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773842 | 0.94 | SMN1; SMN2 (0.50) | MCHR1MEN1KMT2ATDP1MAPT | |
| SCHEMBL6768544 | 0.89 | NPC1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6773863 | 0.88 | GAA (0.47) | MCHR1MEN1KMT2ATDP1MAPT | |
| SCHEMBL6773077 | 0.86 | MCHR1 (0.49) | MCHR1GAANAMPT | |
| SCHEMBL6779944 | 0.86 | HDAC3 (0.48) | DRD2SIGMAR1 | |
| SCHEMBL6778719 | 0.86 | KMT2A (0.48) | KMT2AMAPTNPC1HTTRAB9A | |
| SCHEMBL6773386 | 0.85 | TP53BP1 (0.49) | MEN1KMT2AMAPTGAADRD2 | |
| SCHEMBL6771355 | 0.83 | POLB (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6772103 | 0.82 | MCHR1 (0.51) | MCHR1MEN1KMT2ATDP1MAPT | |
| SCHEMBL6774104 | 0.81 | POLB (0.44) | MEN1KMT2AGAANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |