Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773364 | 0.94 | RXFP1 (0.43) | HDAC3HDAC1MAPTALDH1A1LMNA | |
| SCHEMBL6774104 | 0.90 | POLB (0.44) | HDAC3HDAC1GAAHTTTLR7 | |
| SCHEMBL6773386 | 0.90 | TP53BP1 (0.49) | HDAC3HDAC1MAPTNAMPTALDH1A1 | |
| SCHEMBL6773275 | 0.89 | TRPV1 (0.43) | HDAC3HDAC1EPHX2TLR7MCHR1 | |
| SCHEMBL6774495 | 0.86 | TLR7 (0.43) | TLR7MCHR1 | |
| SCHEMBL6768544 | 0.86 | NPC1 (0.49) | HDAC3HDAC1MAPTNAMPTALDH1A1 | |
| SCHEMBL6773853 | 0.85 | NOS3 (0.46) | HDAC3HDAC1TMEM97SIGMAR1NAMPT | |
| SCHEMBL6780200 | 0.84 | ALDH1A1 (0.50) | HDAC3HDAC1MAPTNAMPTALDH1A1 | |
| SCHEMBL6773253 | 0.84 | GAA (0.41) | MAPTNAMPTALDH1A1LMNAGAA | |
| SCHEMBL6773965 | 0.83 | BRD4 (0.44) | ALDH1A1SMN1; SMN2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |