Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774081 | 0.94 | RAB9A (0.44) | BRD4RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL6775047 | 0.87 | TLR7 (0.44) | BRD4RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL6774104 | 0.85 | POLB (0.44) | RAB9ANPC1KMT2AMEN1TLR7 | |
| SCHEMBL6768544 | 0.83 | NPC1 (0.49) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL6772992 | 0.83 | HDAC3 (0.40) | SMN1; SMN2ALDH1A1TLR7 | |
| SCHEMBL6773853 | 0.83 | NOS3 (0.46) | ALDH1A1KDM4EDRD3TLR7 | |
| SCHEMBL6779944 | 0.83 | HDAC3 (0.48) | DRD2DRD3 | |
| SCHEMBL6773275 | 0.80 | TRPV1 (0.43) | BRD4TLR7 | |
| SCHEMBL6094589 | 0.79 | DYRK1A (0.37) | KDM4ETLR7 | |
| SCHEMBL6773253 | 0.79 | GAA (0.41) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |